choanal atresia การใช้

• There are reported cases of goiter and choanal atresia in fetus.
• Also any condition that causes significant depression of the nasal bridge or midface retraction can be associated with choanal atresia.
• Choanal atresia or stenosis is a narrowing or absence of the choanae, the internal opening of the nasal passages.
• Additional signs and symptoms of Beare Stevenson cutis gyrata syndrome can include a blockage of the nasal passages ( choanal atresia ), overgrowth of the umbilical stump, and abnormalities of the genitalia and anus.
• If this important, early facial embryogenesis fails, it might result in anomalies such as choanal atresia ( absent or closed passage ), medial nasal clefts ( fissures ), or lateral nasal clefts, nasal aplasia ( faulty or incomplete development ), and polyrrhinia ( double nose ).
• This normal, human embryologic development is exceptionally important because the newborn infant breathes through his or her nose during the first 6 weeks of life thus, when a child is afflicted with bilateral choanal atresia, the blockage of the posterior nasal passage, either by abnormal bony tissue or by abnormal soft tissue, emergency remedial action is required to ensure that the child can breathe.
• This normal, human embryologic development is exceptionally important  because the newborn infant breathes through his or her nose during the first 6 weeks of life  thus, when a child is afflicted with bilateral choanal atresia, the blockage of the posterior nasal passage, either by abnormal bony tissue or by abnormal soft tissue, emergency remedial action is required to ensure that the child can breathe.
• Heterozygous loss-of-function mutations in " EFTUD2 " cause "'Mandibulofacial Dysostosis with Microcephaly "'( "'MFDM "'; OMIM # 610536 ), a multiple malformation syndrome comprising progressive microcephaly ( present in all affected individuals ), craniofacial skeletal anomalies, cleft palate, deafness, choanal atresia, small stature, and / or cardiac and thumb anomalies.